OptiMSM Research

OptiMSM is the result of years of research, development and continuous improvement. Bergstrom Nutrition, the makers of OptiMSM, invest in research to support the efficacy and safety of OptiMSM, and uncover new applications and uses to optimize health.

Latest News

Research & Discover

As pioneers in the development of methylsulfonylmethane (MSM) for use in both animal and human nutrition, our ongoing commitment continues to drive research that expands the understanding of MSM’s health benefits. As the leading global MSM supplement manufacturer, we also continue to invest in product innovation and new delivery systems.

Published Studies

OptiMSM has a well-documented record of safety, and has been studied in a wide variety of investigations.

Joint Health

In studies, OptiMSM has been shown to encourage a significant reduction in pain and deterioration of cartilage matrix in joints. Also revealed was the ability of OptiMSM to improve mobility and modify the immune response.


Researchers have observed that OptiMSM may modify pro-inflammatory mechanisms to alleviate exercise-induced soreness and support antioxidant levels in the body. Properties found in OptiMSM can help deter the accumulation of oxidative damage that develops through aging and stress on the body.

Safety & Efficacy

Well-documented and studied for safety and efficacy, OptiMSM is considered safe for humans and animals. There is no known evidence of interactions between OptiMSM and pharmaceuticals, herbs, vitamins or minerals.

View Efficacy Studies

Certified Safe

OptiMSM is the only GRAS-designated MSM on the market. GRAS (“generally recognized as safe”) is the designation given by the FDA to substances considered safe for direct or indirect addition to food.


OptiMSM contains no yeast, dairy, egg, gluten, corn, soy or wheat, and has no added sugar, starch, salt, preservatives, or artificial color, flavor or fragrance. It’s safe for individuals with food allergies and those choosing a vegetarian lifestyle.

No Banned Substances

OptiMSM has undergone thorough testing and audits. This quality has facilitated official registration with Informed-Sport and Informed-Choice to be free of banned substances.

Why OptiMSM?

Unmatched Purity

A proprietary multi-stage distillation process ensures a 99.9% pure product to guarantee a consistent, high-quality MSM.


The only GRAS-designated, Kosher and Halal certified, non-GMO, gluten-free, allergen-free, non-shellfish-derived, vegan MSM backed by extensive toxicology data.


25+ years of manufacturing expertise backed by ISO 9001: 2015 registration, FSSC 220000 certification, HACCP and cGMP compliance.

Easy Formulation

OptiMSM is water-soluble, odorless, stable at high temperatures, dissolves quickly, and has no pH restrictions. It can be used in capsules, tablets, powders, RTM & RTDs.